Job Description

Senior Associate Scientist role within Pfizer's Early Bioprocess Development group focused on optimizing cell line development and fermentation processes for protein subunit vaccines. Position requires hands-on expertise in molecular biology, cell culture techniques, and process optimization with cross-functional collaboration.

Responsibilities

• Optimize cell line development workflows to enhance protein expression, productivity, and biological robustness
• Execute fermentation studies and characterize key performance indicators including cell fitness, yield, and protein quality
• Perform data analysis to establish quantitative correlations between process parameters and protein output metrics
• Present experimental findings and strategic conclusions at cross-functional meetings and prepare technical reports
• Maintain Electronic Laboratory Notebook records and contribute to technical publications while ensuring regulatory compliance

Requirements

• B.S. degree with 3-5 years relevant industry/research experience, or M.S. in bioengineering, biochemistry, or chemical engineering with 0-3 years experience
• Proficiency in aseptic cell culture techniques including passaging, transfection, and viability monitoring
• Experience with flow cytometry, cell sorting cytometers, and FlowJo analysis software
• Hands-on molecular biology expertise: DNA/RNA extraction, PCR, RT-PCR, cloning, gel electrophoresis, SDS-PAGE, western blot, ELISA
• Strong organizational skills, self-motivation, attention to detail, and collaborative communication abilities
• Experience with benchtop or single-use bioreactors (batch, fed-batch) preferred
• NGS sequencing platform knowledge preferred

Compensation: $68,600.00-$114,300.00 base salary plus 7.5% bonus target

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